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5^ec'd PCT/PTO 1J1 0T3CT 2001 

^ PATENT 



266/252 



IN THE UNITED STATES PATENT AND TRADEMARK OFFICE 



In re the Application of: 
Leonard Sciorra et al. 
Serial No.: 09/869,741 
Filed: July 3, 2001 

For: METHODS AND APPARATUS FOR 
SEPARATING BIOLOGICAL 
MATERIALS AND OTHER 
SUBSTANCES 



Group Art Unit: 
Examiner: 



INFORMATION DISCLOSURE STATEMENT 




0 2- 



Commissioner for Patents 
Washington, D.C. 20231 

Dear Sir: 

In compliance with Applicant's duty of disclosure under 37 CFR §§ 1.97 -1.98, the following 
information is brought to the attention of the Examiner. The items are listed on the attached form 
PTO-1449, and copies are enclosed for the convenience of the Examiner. 



The items identified in this Information Disclosure Statement may or may not be "material" 
pursuant to 37 CFR §1.56 and the submission thereof by the Applicant is not to be construed as an 
admission that any such patent, publication or other information referred to therein is material or 

CERTIFICATE OF MAILING 
(37C.F.R. §1.8a) 

Thereby certify that this paper (along with any referred to as being attached or enclosed) is being deposited with the United States Postal Service on the 
date shown below with sufficient postage as First Class Mail in an envelope addressed to the Commissioner for Patents, Washington, D.C. 2023 \ 



Date of Deposit 



1 6(3 hi 




_of Pfigon Mailing Paper 



mi. 



Signatur/of Person Maili 





PATENT 
266/252 



considered to be material (37 CFR § 1.97(h)), or even qualifies as "prior art" under 35 USC § 102 
with respect to this invention unless specifically designated by Applicant as such. 

The filing of this Information Disclosure Statement shall not be construed to mean that a 
search has been made or that no other material information, as defined in 37 CFR 1 .56, exists. 



This Information Disclosure Statement is believed to be timely in that it is being submitted 
under 37 CFR § 1.97(b)(2), that is within three months of entry of the national stage as set forth in 
37 CFR § 1.491. Thus, no fee is required. Should Applicant be in error, however, authorization is 
given to charge any fee required for the consideration of this paper to counsel's Deposit Account 
No. 12-2475. 



Respectfully submitted, 



LYON & LYON LLP 



Dated: October 3, 2001 





22249 



LYON & LYON LLP 

633 W. Fifth Street, Suite 4700 

Los Angeles, CA 90071 



PATENT TRADEMARK OFFICE 



Tel: (213) 489-1600 
Fax: (213)955-0440 



2 



FOR/Vf PTO-144£ _ 

LIST OF PATENTS AND OTHEWBmS FOR APPLICANT'S 
^TD^Wf ORMATION DISCLOSURE STATEMENT 

/ ^n(Use several sheets if necessary) 


ATTY. DOCKET NO. 

266/252 


SERIAL NO. 

09/869,741 


APPLICANT 

Sciorra, Leonard et al. 


FILING DATE: 

July 3, 2001 


GROUP: 



& £ U.S. PATENT DOCUMENTS 


El^MINER 




DOCUMENT NUMBER 


DATE 


NAME 


CLASS 


SUB 
CLASS 


FILING 
DATE 




Al 


5,993,665 


11/30/99 


Terstappen 










A2 


5,939,964 


8/17/99 


Domigan 










A3 


5,779,892 


7/14/98 


Miltenyi et al. 










A4 


5,191,223 


3/2/93 


Munekata 










A5 


5,770,388 


6/23/98 


Vorpahl 










A6 


5,508,164 


4/16/96 


Kausch et al. 










A7 


5,200,084 


4/6/93 


Liberti et al. 










A8 


5,466,574 


11/14/95 


Liberti, et al. 










A9 


4,935,147 


6/19/90 


Ullman et al. 










A10 


5,536,475 


7/16/96 


Moubayed et al. 










All 


5,224,604 


7/6/93 


Duczmal et al. 










A12 


5,876,593 


3/2/99 


Liberti et al. 










A13 


5,691,208 


11/25/97 


Miltenyi et al. 










A14 


5,795,470 


8/18/98 


Wang et al. 










A15 


5,541,072 


7/30/96 


Wang et al. 










A16 


4,017,385 


4/12/77 


Morton et al. 










A17 


5,437,987 


8/1/95 


Tens et al. 










A18 


5,275,933 


1/4/94 


Teng et al. 










A19 


4,241,176 


12/23/80 


Avrameas et al. 










A20 


4,375,407 


3/1/83 


Kronick 










A21 


5,186,827 


2/16/93 


Liberti et al. 










A22 


5,340,749 


8/23/94 


Fujiwara et al. 









EXAMINER: 



DATE CONSIDERED: 



EXAMINER: Initial if reference is considered, whether or not citation is in conformance with MPEP 609; 
Draw line through citation if not in conformance and not considered. Include a copy of this form with next 
communication to applicant 



Information Disclosure Statement - Section 9 PTO-1449 



Page 1 of 2 



FORVf PTO-1449 

* 

LIST OF PATENTS AND OTHEl^PMS FOR APPLICANT'S 
INFORMATION DISCLOSURE STATEMENT 



(Use several sheets if necessary) 




ATTY. DOCKET NO. 

266/252 



SERIAL NO. 

09/869,741 



APPLICA1 

Sciorra, Leonard et al. 



FILING DATE: 

July 3, 2001 



GROUP: 



5,236,824 



8/17/93 



Fujiwara et al. 



5,279,936 



1/18/94 



Vorpahl 



A25 



5,004,539 



4/2/91 



Colwell, Jr. 



A26 



5,543,289 



8/6/96 



Miltenyi 



A27 



5,122,269 



6/16/92 



De Reuver 



A28 



4,772,383 



9/20/88 



Christensen 



A29 



4,594,160 



6/10/86 



Heitmann et al. 



FOREIGN PATENT DOCUMENTS 


EXAMINER 
INITIAL 




DOCUMENT NUMBER 


DATE 


COUNTRY 


CLASS 


SUB 
CLASS 


TRANSLATION 
YES NO 




Bl 


PCT WO 95/141 18 


6/26/95 


PCT 















































OTHER DOCUMENTS (Including Author, Title, Date, Pertinent Pages, etc.) 




CI 


Cheung, M. et al., "Prenatal diagnosis of sickle cell anaemia and thalassaemia by analysis of fetal cells in 
maternal blood", Nature Genetics, Volume 14, 1996, pgs. 264-268 




C2 


Bier, M. "Electrophoresis", Chapter Seventeen, pgs. 497- 526 



EXAMINER: 



DATE CONSIDERED: 



EXAMINER: Initial if reference is considered, whether or not citation is in conformance with MPEP 609; 
Draw line through citation if not in conformance and not considered. Include a copy of this form with next 
communication to applicant 



Information Disclosure Statement - Section 9 PTO-1449 



Page 2 of 2